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Recombinant human PRMT5

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DNA methylation of the Tacr2 gene in a CUMS model of depr...

BRAIN RESEARCH
Catalog Number
Format
Order
C23010107
10 µg
info@diagenode.com

Full length recombinant human N-terminal Flag tagged PRMT5 (Protein Arginine Methyltransferase 5) protein, produced in SF9 insect cells.

    Product Description

    PRMT5 recombinant protein

    Other names

    SKB1, HRMT1L5, SKB1Hs, IBP72, JBP1

    Target description

    PRMT5 (UniProt/Swiss-Prot entry O14744) is an arginine methyltransferase that can both catalyze the monomethylation and symmetrical dimethylation of arginine residues with a preference for the formation of monomethylarginine, in a variety of proteins including SNRPD1, SNRPD3, SUPT5H, MBP, PIWIL1, PIWIL2, PIWIL4, HOXA9, SRGAP2 and histone H2A, H4 and H3. Histone H2A and H4 are methylated at R3 during germ cell development, whereas histone H3 is methylated at R8, probably leading to transcriptional repression.

    Concentration

    0.5µg/µl

    Specificity 

    Human

    Purity

    Purified using FPLC, >95% purity as determined by SDS-PAGE.

    Storage Buffer

    20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.

    Storage

    Store at-80°C; guaranteed stable for 2 years from date of receipt when stored properly.

    Precautions: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

    Quality Control

    Figure 1.
    SDS page of the PRMT5 recombinant protein. The position of the protein of interest is indicated on the right; the marker (in kDa) is shown on the left.

     Documents
    PRMT5 recombinant protein TDS DATASHEET
    Datasheet of PRMT5 recombinant protein     		Download
     Publications

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