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Recombinant human Hp1 gamma (CBX3)

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BRAIN RESEARCH
Catalog Number
Format
Order
C23010103
25 µg
info@diagenode.com

Full length recombinant human N-terminal His tagged HP1g (Heterochromatin Protein 1 Homolog Gamma) protein, produced in E. coli.

    Product Description

    HP1g recombinant protein

    Other names

    CBX3, HECH, HP1 gamma

    Target description

    HP1 gamma (UniProt/Swiss-Prot entry Q13185) is a component of heterochromatin. It recognizes and binds to histone H3 tails methylated at 'Lys-9', leading to epigenetic repression of transcription. HP1g may also interact with lamin B receptor (LBR), thereby contributing to the association of the heterochromatin with the inner nuclear membrane. HP1g is recruited to sites of ultraviolet-induced DNA damage and double-strand breaks and may be associated with microtubules and mitotic poles during mitosis.

    Concentration

    0.5µg/µl

    Specificity 

    Human

    Purity

    Purified using FPLC, >98% purity as determined by SDS-PAGE.

    Storage Buffer

    20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.

    Storage

    Store at-80°C; guaranteed stable for 2 years from date of receipt when stored properly.

    Precautions: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

    Quality Control

    Figure 1.
    SDS page of the HP1γ recombinant protein. The position of the protein of interest is indicated on the right; the marker (in kDa) is shown on the left.

     Documents
    HP1γ recombinant protein TDS DATASHEET
    Datasheet of HP1γ recombinant protein     		Download
     Publications

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