Recombinant human Hp1 alpha (CBX5)
Full length recombinant human N-terminal His tagged HP1a (Heterochromatin Protein 1 Homolog Alpha) protein, produced in E. coli.
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C23010102
Recombinant human Hp1 beta (CBX1)
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C23010106
Recombinant human MeCp2
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C23010109
Recombinant human Tif1 alpha (Trim24)
Product Description
HP1a recombinant protein
Other names
CBX5, MOD1, M31, P25b
Target description
HP1 alpha (UniProt/Swiss-Prot entry P45973) is a component of heterochromatin. It recognizes and binds to histone H3 tails methylated at 'Lys-9', leading to epigenetic repression of transcription. HP1 alpha may also interact with lamin B receptor (LBR), thereby contributing to the association of the heterochromatin with the inner nuclear membrane. Further, HP1 alpha is involved in the formation of a functional kinetochore through interaction with MIS12 complex proteins.
Concentration
0.5µg/µl
Specificity
Human
Purity
Purified using FPLC, >98% purity as determined by SDS-PAGE.
Storage Buffer
20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
Storage
Store at-80°C; guaranteed stable for 2 years from date of receipt when stored properly.
Precautions: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Quality Control
Figure 1.
SDS page of the HP1α recombinant protein. The position of the protein of interest is indicated on the right; the marker (in kDa) is shown on the left.
Documents
| Recombinant human Hp1 alpha (CBX5) DATASHEET Full length recombinant human N-terminal His tagged HP1a (Heterochromatin Protein 1 Homolog Alpha... | Download |
Publications
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