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Recombinant Histone H3.3

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Catalog Number
Format
Order
C23010008
100 μg

Full length recombinant histone H3.3, produced in E. coli.

    Protein description

    Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. The histone variant H3.3 replaces conventional H3.1 in a wide range of nucleosomes in active genes. H3.3 constitutes the predominant form of histone H3 in non-dividing cells.

    Quality control

    Figure 1.
    SDS page of the Recombinant Histone H3.3. The position of the protein of interest is indicated on the right; the marker (in kDa) is shown on the left.

    Figure 2.
    ESi-TOF analysis of Recombinant Histone H3.3

     Documents
    C23010008 histone H3 3 DATASHEET
    C23010008 histone H3 3 tds
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     Publications

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