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Recombinant Histone H2A.Z

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BRAIN RESEARCH
Catalog Number
Format
Order
C23010006
100 μg
info@diagenode.com

Full length recombinant histone H2A.Z, produced in E. coli.

    Protein description

    Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. The histone variant H2A.Z replaces conventional H2A in a subset of nucleosomes. H2AZ is involved in transcriptional regulation, antisilencing, silencing, and genome stability. It functions as a key regulator of chromatin function and plays an essential role during mammalian development.

    Quality control

    Figure 1.
    SDS page of the Recombinant Histone H2A.Z. The position of the protein of interest is indicated on the right; the marker (in kDa) is shown on the left.

    Figure 2.
    ESi-TOF analysis of Recombinant H2A.Z.

     Documents
    C23010006 histone H2AZ DATASHEET
    C23010006 histone H2AZ tds    		 Download
     Publications

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